Scientists Create See-Through Fish, Watch Cancer Grow

Through cross-breeding, scientists have created a zebra-fish with a transparent skin so that they can actually see the insides of the fish. Zebra fish are genetically similar to humans in a number of ways, and hence serve as good subjects for experiments like this. These are now being used to understand cancer. Excerpt:

White created the transparent fish, which he nicknamed Casper, by mating two existing zebrafish breeds, one that lacked a reflective skin pigment and the other without black pigment. The offspring had only yellow skin pigment, essentially appearing clear.

In one experiment, White and his colleagues inserted a fluorescent melanoma tumor into the abdominal cavity of the transparent fish. By observing the fish under a microscope, they found that the cancer cells started spreading within five days. White could actually see individual cells spreading.

See full article. They also have a picture of the fish for you to ogle.

15 Years of Java experience required…

This post has a very interesting take on the “Required: X years of experience with Y” concept:

Programming platform experience is like knowing your way around the kitchen. Where are the knives, what size plates do we have, and what spices are available. It’s very useful for getting things done without having to search high and low for every little thing. But it’s also an asset with a cut-off point of diminished returns. Once you have a reasonably good idea where things are, it’s no longer the bottleneck in your culinary performance.

Like chefs, like programmers. Peopleware quotes a study that six months seemed to be the cut-off point for programmers. Once they had six months under their belt, the platform knowledge was no longer the bottleneck in their abilities.

[…]
Which leads me to my point: Requiring X years of experience on platform Y in your job posting is, well, ignorant. As long as applicants have 6 months to a year of experience, consider it a moot point for comparison. Focus on other things instead that’ll make much more of a difference. Platform experience is merely a baseline, not a differentiator of real importance.

See full article.